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style="text-indent: 32px; text-align: justify; line-height: 2em;"><span lang="EN-US" style="font-size:16px;font-family:瀹嬩綋">1. </span><span style="font-size:16px;font-family:瀹嬩綋">鐮旂┒鏂瑰悜锛欬/span></p> <p style="text-indent: 32px; text-align: justify; line-height: 2em;"><span style="font-size:16px;font-family:瀹嬩綋">绯栧翱鐥匋span lang="EN-US">2</span>鍨嬶紝鑲ヨ儢鐥囷紝鑴傝偑浠h阿锛屾鑹茶剛鑲唬璋紱浠ュ強鍩虹鍖诲锛屼复搴婂尰瀛︾浉鍏崇爺绌迭/span></p> <p style="text-indent: 32px; text-align: justify; line-height: 2em;"><span lang="EN-US" style="font-size:16px;font-family:瀹嬩綋">2. </span><span style="font-size:16px;font-family:瀹嬩綋">搴旇仒鏉′欢锛欬/span></p> <p style="text-indent: 32px; text-align: justify; line-height: 2em;"><span lang="EN-US" style="font-size:16px;font-family:瀹嬩綋">1</span><span style="font-size:16px;font-family:瀹嬩綋">锛夊凡鑾峰緱鍗氬+瀛︿綅锛堝尰瀛︼紝鐢熺墿鍖诲锛岀敓鍛界瀛︼紝鐢熺墿鎶€鏈紝鐢熺墿淇℃伅瀛︾瓑鐩稿叧涓撲笟锛夋垨鏈櫌涓村簥鍖诲<span lang="EN-US">8</span>骞村埗搴斿眾姣曚笟鐢燂紱</span></p> <p style="text-indent: 32px; text-align: justify; line-height: 2em;"><span lang="EN-US" style="font-size:16px;font-family:瀹嬩綋">2</span><span style="font-size:16px;font-family:瀹嬩綋">锛夊绉戝鐮旂┒鏈夋祿鍘氬叴瓒o紝鏈夊洟闃熷悎浣滄剰璇嗗強鐙珛鎬濊€冭兘鍔涳紝鍏峰涓€瀹氱殑瀛︽湳姘村钩鍜岀鐮旇兘鍔涳紱鍏峰鑻辨枃闃呰鍜屽啓浣滆兘鍔涳紱</span></p> <p style="text-indent: 32px; text-align: justify; line-height: 2em;"><span lang="EN-US" style="font-size:16px;font-family:瀹嬩綋">3</span><span style="font-size:16px;font-family:瀹嬩綋">锛夊勾榫勪竴鑸笉瓒呰繃<span lang="EN-US">35</span>宀侊紝绗竴瀛﹀巻鏈锛圏span lang="EN-US">985</span>锛孅span lang="EN-US">211</span>閲嶇偣澶у锛夛紝鍗氬+姣曚笟鍘熷垯涓婁笉瓒呰繃<span lang="EN-US">3</span>骞达紝韬綋鍋ュ悍銆侟/span></p> <p style="text-indent: 32px; text-align: justify; line-height: 2em;"><span lang="EN-US" style="font-size:16px;font-family:瀹嬩綋">3. </span><span style="font-size:16px;font-family:瀹嬩綋">宸ヤ綔寰呴亣锛欬/span></p> <p style="text-indent: 32px; text-align: justify; line-height: 2em;"><span style="font-size:16px;font-family:瀹嬩綋">棰勬湡骞磋柂<span lang="EN-US">25-30</span>涓嘃/span></p> <p style="text-indent: 32px; text-align: justify; line-height: 2em;"><span lang="EN-US" style="font-size:16px;font-family:瀹嬩綋">1</span><span style="font-size:16px;font-family:瀹嬩綋">锛夊尰闄㈠皢缁欎簣鍗氬+鍚嶞span lang="EN-US">18</span>涓囧勾钖紝骞舵寜鐓у浗瀹舵爣鍑嗙即绾充簲闄╀竴閲戙€傚悎浣 瀵煎笀鎸堻span lang="EN-US">3</span>涓囧厓<span lang="EN-US">/</span>骞磋捣浠樿柂閰紝涓婁笉灏侀《锛汓/span></p> <p style="text-indent: 32px; text-align: justify; line-height: 2em;"><span lang="EN-US" style="font-size:16px;font-family:瀹嬩綋">2</span><span style="font-size:16px;font-family:瀹嬩綋">锛夊ぇ瀛﹀崥澹悗鍦ㄧ珯鏈熼棿锛屽尰闄㈡彁渚涘崥澹悗鍏瘬锛屾湭鑳藉叆浣忚€咃紝缁欎簣<span lang="EN-US">1000</span>鍏傸span lang="EN-US">/</span>鏈堢殑绉熸埧琛ュ姪锛汓/span></p> <p style="text-indent: 32px; text-align: justify; line-height: 2em;"><span lang="EN-US" style="font-size:16px;font-family:瀹嬩綋">3</span><span style="font-size:16px;font-family:瀹嬩綋">锛夋牴鎹繘绔欓潰璇曟椂杈惧埌鐨勬爣鍑嗭紝缁欎簣<span lang="EN-US">3.6</span>涓嘃span lang="EN-US">/</span>骞存垨<span lang="EN-US">6</span>涓嘃span lang="EN-US">/</span>骞寸殑鐗瑰埆濂栧姳銆備笟缁╃獊鍑鸿€咃紝鍑虹珯鍚庡笇鏈涚暀闄㈢暀鏍″伐浣滅殑锛屽尰闄㈠皢鎻愪緵涓€鍒囦究鍒╋紱</span></p> <p style="text-indent: 32px; text-align: justify; line-height: 2em;"><span style="font-size:16px;font-family:瀹嬩綋">寰呴亣浼樺帤锛屾杩庡悇浣嶅織鍚岄亾鍚堢殑鍚屽鎴栧悓浜嬪姞鍏ユ垜浠€侟/span></p> <p style="text-indent:32px"><br></p> <p style="text-indent:32px"><br></p> <p style="text-indent: 32px; text-align: justify; line-height: 2em;"><span style="font-size:16px;font-family:瀹嬩綋">闄堝媷鏁欐巿鍥㈤槦鍙婂尰闄㈠钩鍙扮畝浠婞/span></p> <p style="text-indent: 32px; text-align: justify; line-height: 2em;"><span style="font-size:16px;font-family:瀹嬩綋">闄堝媷鏁欐巿鏄崕涓鎶€澶у鍚屾祹鍖诲闄㈤檮灞炲悓娴庡尰闄㈡捣澶栧紩杩涗汉鎵嶏紝寰峰浗娉㈡仼澶у鍖诲鍜岃嚜鐒剁瀛﹀崥澹紝缇庡浗鍔犲窞澶у鏃ч噾灞卞垎鏍★紙<span lang="EN-US">UCSF</span>锛夊尰瀛︿腑蹇冨崥澹悗锛屾嫢鏈夊椤圭爺绌舵垚鏋滐紝鍦ㄥ浗闄呰憲鍚嶆潅蹇椾笂鍙戣〃<span lang="EN-US">SCI</span>瀛︽湳璁烘枃鍗佷綑绡囷紝褰卞搷鍥犲瓙<span lang="EN-US">180</span>澶氬垎銆傚叾涓互绗竴浣滆€呮垨閫氳浣滆€呭彂琛ㄤ簡鏁扮瘒锛屽寘鎷?span lang="EN-US">Nature,Nature Communications,Cell Metabolism</span>绛夈€侟/span></p> <p style="text-indent: 32px; text-align: justify; line-height: 2em;"><span style="font-size:16px;font-family:瀹嬩綋">鍗庝腑绉戞妧澶у闄勫睘鍚屾祹鍖婚櫌浣滀负鍗庝腑鍦板尯鏈€澶х殑鍖婚櫌锛屾敞閲嶅尰鐤楋紝绉戠爺鍙婃暀瀛﹀悇鏂归潰鐨勪汉鎵嶅煿鍏汇€傚尰闄㈡嫢鏈夊浗瀹朵复搴婂尰瀛︾爺绌朵腑蹇傸span lang="EN-US">1</span>涓紝鍗敓閮ㄩ噸鐐瑰疄楠屽<span lang="EN-US">2</span>涓紝鏁欒偛閮ㄩ噸鐐瑰疄楠屽<span lang="EN-US">2</span>涓€傛箹鍖楃渷閲嶇偣瀹為獙瀹|span lang="EN-US">1</span>涓紝婀栧寳鐪佷复搴婂尰瀛︾爺绌朵腑蹇傸span lang="EN-US">5</span>涓€傛嫢鏈変腑鍥界瀛﹂櫌闄㈠+<span lang="EN-US">1</span>鍚嶃€佷腑鍥藉伐绋嬮櫌闄㈠+<span lang="EN-US">1</span>鍚嶃€侀暱姹熷鑰匋span lang="EN-US">4</span>鍚嶃€佸浗瀹舵澃鍑洪潚骞寸瀛﹀熀閲慄span lang="EN-US">8</span>鍚嶃€佸浗瀹跺崈浜鸿鍒扅span lang="EN-US">1</span>鍚嶃€佸浗瀹迭span lang="EN-US">鈥淈/span>鐧惧崈涓嘃span lang="EN-US">鈥滭/span>浜烘墠宸ョ▼<span lang="EN-US">4</span>鍚嶃€?span lang="EN-US">鈥 973鈥 </span>棣栧腑<span lang="EN-US">2</span>鍚嶏紝鍥藉闈掑勾鍗冧汉<span lang="EN-US">5 </span>鍚嶏紝鏁欒偛閮ㄦ柊涓栫邯浼樼浜烘墠<span lang="EN-US">11</span>鍚嶃€傛暀鑲查儴鍒涙柊鍥㈤槦<span lang="EN-US">2</span>涓€傚尰闄㈢幇鏈夋暀鑲查儴閲嶇偣瀛︾<span lang="EN-US">8</span>涓紝鏁欒偛閮ㄩ噸鐐瑰煿鑲插绉慄span lang="EN-US">3</span>涓€傚埌鐩墠涓烘鎴戦櫌宸叉湁<span lang="EN-US">31</span>涓笓涓氳幏寰楄嵂鐗╀复搴婅瘯楠岃祫鏍笺€侟/span></p> <p 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